Program Description
An estimated 100,000 individuals in the United States are living with sickle cell disease (SCD), which is a group of inherited red blood cell (RBC) disorders that cause RBCs to form a sickle or crescent shape and die prematurely or contribute to vaso-occlusive crises due to the obstructions caused by the sickled cells. Patients with SCD often experience challenges including those associated with access to treatment, life-threatening complications, and reduced quality of life that can make disease management difficult. If not managed properly, the chronic state and breakdown of RBCs in SCD can progress to organ damage and failure. This program will present the safety and efficacy of newer and emerging treatments for SCD, including potential gene therapies that aim to increase hemoglobin levels. Pharmacists play a critical role as members of the multidisciplinary team and can assist with increasing awareness of new and emerging therapies for SCD and improving the care of patients. Considerations for educating patients on SCD and potential treatment options, as well as important medication-specific pearls, such as addressing potential safety concerns to prevent adverse outcomes in patients, will be discussed.
Target audience: Health-system and specialty pharmacists
Type of activity: Application
Release date: October 19, 2022
Expiration date: December 19, 2022
Time to complete activity: 1.0 hour
Fee: Free
Educational Objectives
At the completion of this activity, participants will be able to:
- Explain the role of hemolysis and anemia in the development of end organ damage and disease progression in sickle cell disease (SCD)
- Examine newer and emerging treatments to address the underlying disease state in SCD, including the mechanism of action, safety and efficacy data, place in therapy, and real-world utility
- Identify effective strategies in the management of SCD and the role of the pharmacist on the multidisciplinary team
Lindsey Dayer, PharmD, BCACP
Associate Professor, Department of Pharmacy Practice
Director of Health-System Experiential Rotations
University of Arkansas for Medical Sciences
Little Rock, Arkansas
Pharmacy Times Continuing Education™ is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. This activity is approved for 1.0 contact hour (0.10 CEU) under the ACPE universal activity number 0290-0000-22-394-L01-P. The activity is available for CE credit through December 19, 2022.
Instructions for Completing the Activity and Receiving CPE Credit
To receive CPE credit, participants must complete the pretest, review the activity in its entirety, complete the posttest, and complete the online activity evaluation. After successful completion of the online activity evaluation, you can submit your credit to CPE Monitor. You may view your credit within 48 hours at www.mycpemonitor.net. All participants must request credit before the activity expiration date. CE credit will not be issued after this date.
Disclosures
The following contributors have no relevant financial relationships with commercial interests to disclose:
Faculty
Lindsey Dayer, PharmD, BCACP
Pharmacy Times Continuing Education™ Planning Staff—Jim Palatine, RPh, MBA; Maryjo Dixon, RPh; Liza Patel, PharmD, RPh; Abigail Dill; Susan Pordon; Brianna Winters; and Chloe Taccetta.
An anonymous peer reviewer was used as part of content validation and conflict resolution. The peer reviewer has no relevant financial relationships with commercial interests to disclose.
Educational Disclaimer
CPE activities are offered solely for educational purposes and do not constitute any form of professional advice or referral. Discussions concerning drugs, dosages, and procedures may reflect the clinical experience of the author(s) or they may be derived from the professional literature or other sources and may suggest uses that are investigational in nature and not approved labeling or indications. Participants are encouraged to refer to primary references or full prescribing information resources.
For questions about this internet CPE activity, please contact:
[email protected]
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