Program Description
Hypertrophic cardiomyopathy (HCM) is a condition wherein the muscles of the heart thicken or enlarge with left ventricular hypertrophy, which may be due to sarcomere gene variation. HCM is quite common, seen in 1 in every 500 people worldwide and in 600,000 individuals in the United States alone. Symptomatic treatment has been the mainstay of managing HCM, but recently 1 approved medication has been shown to treat the underlying cause of HCM, with several additional therapies under investigation. Such medication leads to improved quality of life and reduced overall costs for patients. Pharmacists play a key role in managing medications, screening for drug interactions and possible adverse reactions, and making recommendations for optimal treatment. Pharmacists should be informed and aware of newly available methods for the management of HCM, as they can be influential in providing the best possible care for their patients. This activity will equip pharmacists with knowledge of the disease characteristics of HCM, new and emerging medications, and opportunities to achieve optimal patient care.
Target audience: Health-system and retail pharmacists
Type of activity: Application
Release date: October 1, 2022
Expiration date: March 1, 2024
Time to complete activity: 2.0 hours
Fee: Free
Educational Objectives
At the completion of this activity, participants will be able to:
- Explain the underlying pathophysiologic mechanisms and presentation of hypertrophic cardiomyopathy (HCM) along with comorbidities that may place patients at risk for disease progression
- Analyze the mechanism of action and clinical data for recently approved and emerging therapies for HCM as well as patient populations eligible for treatment with novel agents
- Identify opportunities for pharmacists within health systems to facilitate access to medications and support patients with HCM in the initiation of therapy, monitoring of adverse effects, and adherence management

Ryan G. D’Angelo, PharmD, BCPS
Clinical Pharmacy Specialist – Cardiology
Department of Pharmacy
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania

Pharmacy Times Continuing Education™ is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. This activity is approved for 2.0 contact hours (0.20 CEU) under the ACPE universal activity number 0290-0000-22-435-H01-P. The activity is available for CE credit through March 1, 2024.
Instructions for Completing the Activity and Receiving CPE Credit
To receive CPE credit, participants must complete the pretest, review the activity in its entirety, complete the posttest, and complete the online activity evaluation. After successful completion of the online activity evaluation, you can submit your credit to CPE Monitor. You may view your credit within 48 hours at www.mycpemonitor.net. All participants must request credit before the activity expiration date. CE credit will not be issued after this date.
Disclosures
The following contributors have no relevant financial relationships with commercial interests to disclose:
Faculty
Ryan G. D’Angelo, PharmD, BCPS
Pharmacy Times Continuing Education™ Planning Staff—Jim Palatine, RPh, MBA; Maryjo Dixon, RPh; Dipti Desai, PharmD, MBA, CHCP; Abigail Dill; Susan Pordon; Brianna Winters; and Chloe Taccetta.
An anonymous peer reviewer was used as part of content validation and conflict resolution. The peer reviewer has no relevant financial relationships with commercial interests to disclose.
Educational Disclaimer
CPE activities are offered solely for educational purposes and do not constitute any form of professional advice or referral. Discussions concerning drugs, dosages, and procedures may reflect the clinical experience of the author(s) or they may be derived from the professional literature or other sources and may suggest uses that are investigational in nature and not approved labeling or indications. Participants are encouraged to refer to primary references or full prescribing information resources.
For questions about this internet CPE activity, please contact:
[email protected]
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