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Soluble Guanylate Cyclase Stimulators in the Management of Worsening Heart Failure With Reduced Ejection Fraction

August 24, 2023 | 1:00 PM & 6:00 PM ET

This activity is part 2 in a 3-part webinar curriculum.

Program Description

Heart failure (HF) is associated with dysfunction in a number of pathways, including impaired synthesis of nitric oxide and decreased activity of soluble guanylate cyclase. While a range of therapies is available, each requires specific patient education and monitoring considerations for long-term cardiovascular management. This webinar will focus on the role of soluble guanylate stimulators in the management of HF and clinical data supporting the use of these agents in reducing hospitalizations in patients with HF with reduced ejection fraction. Considerations for the administration and dosing of soluble guanylate stimulators as well as their place in guideline-directed medical therapy for patients with HF will be reviewed.


Target audience: Health-system and retail pharmacists

Type of activity: Application
Release date: August 24, 2023
Expiration date: October 24, 2023

Time to complete activity: 1.0 hour

Learner level: Foundational, Intermediate
Fee: Free

Educational Objectives

At the completion of this activity, participants will be able to:

  • Explore updates to the guideline recommendations for management of worsening heart failure with reduced ejection fraction (HFrEF)
  • Examine the mechanism of action of soluble guanylate cyclase stimulators and their potential benefits in the management of worsening HFrEF
  • Analyze the clinical trial data associated with the use of soluble guanylate cyclase stimulators and their dosing and administration

This activity is supported by an educational grant from Merck & Co, Inc, Rahway, NJ, USA.

What's Included
  • Access your activities anytime, anywhere, with a computer, tablet or smartphone
  • Free access with a PTCE account
  • Pharmacy education designed to improve patient care

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