Advances in Pharmacotherapy for Excessive Daytime Sleepiness Due to Narcolepsy

Program Description
Excessive daytime sleepiness (EDS) due to narcolepsy is a chronic neurological condition resulting from a dysregulated sleep-wake cycle. EDS is characterized by an inability to maintain wakefulness and alertness during waking hours, and episodes of sleep occurring unintentionally or at inappropriate times. EDS is a serious condition that requires lifelong treatment and management of contributing factors. With the recent advancements in medicine, the American Academy of Sleep Disorders updated treatment guidelines based on improved efficacy, mechanism of action, and convenient dosing schedules. This article will highlight the challenges pharmacists face when identifying and treating EDS and address the importance of educating patients on medication safety and adherence.

Target Audience: Health System Pharmacist, Retail Pharmacist, Specialty Pharmacist

Type of Activity: Application
Release date: December 4, 2023
Expiration date: December 4, 2024

Time to complete activity: 2.0 hours
Fee: Free

Educational Objectives

At the completion of this activity, participants will be able to:

• Identify the factors that contribute to disrupted nighttime sleep and nocturnal symptoms related to narcolepsy and excessive daytime sleepiness (EDS)
• Explain the effects of medications in addressing narcolepsy and EDS to improve patient health and well-being
• Apply the information to individualize treatment using a shared decision model to improve medication adherence and persistence, and provide better monitoring and education services to patients to improve outcomes

Pharmacy Times Continuing Education^™ is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. This activity is approved for 2.0 contact hours (0.20 CEU) under the ACPE universal activity number 0290-0000-23-420-H01-P. The activity is available for CE credit through December 4, 2024.

Instructions for Completing the Activity and Receiving CPE Credit

To receive CPE credit, participants must complete the pretest, view the activity in its entirety, complete the posttest, and complete the online activity evaluation. After successful completion of the online activity evaluation, you can submit your credit to CPE Monitor. You may view your credit within 48 hours at www.mycpemonitor.net. All participants must request credit before the activity expiration date. CE credit will not be issued after this date.

Disclosures

Marilyn N. Bulloch, PharmD, BCPS, FCCM, SPP, has the following relevant financial relationships with commercial interests to disclose:

Grant Support: Alabama Department of Public Health – COVID-19

Consultant: Alabama Medicaid DUR Board

The following contributors have no relevant financial relationships with commercial interests to disclose:

Pharmacy Times Continuing Education^™ Planning Staff—Jim Palatine, RPh, MBA; Maryjo Dixon, RPh, MBA; Dipti Desai, PharmD, MBA, CHCP; Abigail Dill; Susan Pordon; Brianna Winters; Chloe Taccetta; and Rebecca Green have no relevant financial relationships with commercial interests to disclose.

Medical reviewer Megan Maroney, PharmD, BCPP, has the following relevant financial relationships with commercial interests to disclose:

• Consultant: Novus Medical Education
• Speaker: Otsuka Pharmaceuticals

Other (advisory board): Boehringer Ingelheim, Biogen, Sage Therapeutics

An anonymous peer reviewer was part of the content validation and conflict resolution and has no relevant financial relationships with commercial interests to disclose.

Educational Disclaimer
CPE activities are offered solely for educational purposes and do not constitute any form of professional advice or referral. Discussions concerning drugs, dosages, and procedures may reflect the clinical experience of the author(s) or they may be derived from the professional literature or other sources and may suggest uses that are investigational in nature and not approved labeling or indications. Participants are encouraged to refer to primary references or full prescribing information resources.

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[email protected]
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