This activity was originally broadcast on November 12, 2022 as part of the Directions in Oncology Pharmacy virtual conference series.
Program Description
Recent advances have greatly improved identification of molecular markers for diagnosis of acute myeloid leukemia (AML). Accurate prognosis at time of diagnosis is essential as it impacts clinical decisions. Unfortunately, older patients, ones with therapy-related AML/antecedent myelodysplastic syndrome, and men typically experience worse survival outcomes. This program will focus on clinical evidence updates for therapies utilized for induction and maintenance treatment of AML and corresponding changes in clinical practice guidelines. Novel agents have been associated with unique adverse effects (AEs), warranting careful patient monitoring. Pharmacist involvement in AML treatment, therapeutic adjustments of pharmacotherapy, AE prevention approaches, and unique toxicity management strategies will be examined.
Target audience: Oncology pharmacists, health-system pharmacists, and specialty pharmacists
Type of activity: Knowledge
Release date: November 30, 2022
Expiration date: November 30, 2023
Time to complete activity: 0.75 hours
Fee: Free
Educational Objectives
At the completion of this activity, participants will be able to:
- List pharmacologic properties of newer targeted agents in acute myeloid leukemia (AML) treatment
- Outline recent clinical evidence for the treatment of AML
- Detail different treatment approaches for induction, consolidation, and maintenance therapy of AML based on disease risk factors and guideline recommendations
- Recall management strategies for common adverse effects associated with newer targeted therapies in AML

Jessie Signorelli, PharmD, BCOP
Clinical Pharmacist Specialist – Hematology/Oncology
Massachusetts General Hospital
Boston, Massachusetts

Pharmacy Times Continuing Education™ is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. This activity is approved for 0.75 contact hours (0.075 CEU) under the ACPE universal activity number 0290-0000-22-583-H01-P. The activity is available for CE credit through November 30, 2023.
Instructions for Completing the Activity and Receiving CPE Credit
To receive CPE credit, participants must complete the pretest, review the activity in its entirety, complete the posttest, and complete the online activity evaluation. After successful completion of the online activity evaluation, you can submit your credit to CPE Monitor. You may view your credit within 48 hours at www.mycpemonitor.net. All participants must request credit before the activity expiration date. CE credit will not be issued after this date.
Disclosures
Jessie Signorelli, PharmD, BCOP, has the following relevant financial relationships with commercial interests to disclose:
- Bristol Myers Squibb: Advisory board
- AbbVie: Presenter
Pharmacy Times Continuing Education™ Planning Staff: Jim Palatine, RPh, MBA; Amy Seung, PharmD, BCOP, FHOPA; Evelina Kolychev, PharmD, BCOP; Crissy Wilson; Chloe Taccetta; Susan Pordon; and Brianna Winters have no financial relationships with commercial interests to disclose.
Anonymous peer reviewers have been used as part of content validation and conflict resolution. The peer reviewers have no relevant financial relationships with commercial interests to disclose.
Educational Disclaimer
CPE activities are offered solely for educational purposes and do not constitute any form of professional advice or referral. Discussions concerning drugs, dosages, and procedures may reflect the clinical experience of the author(s) or they may be derived from the professional literature or other sources and may suggest uses that are investigational in nature and not approved labeling or indications. Participants are encouraged to refer to primary references or full prescribing information resources.
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[email protected]
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