This activity was originally presented at the 2026 Breast
Cancer Day of Education.
In collaboration with HOPA & COA.
Program Description
The uptake of antibody-drug conjugates (ADCs) across advanced breast cancer subtypes requires pharmacist expertise to navigate this expanding treatment landscape. Recent ADC development utilizing tumor-specific monoclonal antibodies paired with highly potent cytotoxic payloads via advanced linker technologies has resulted in greater efficacy. This session will equip oncology pharmacists with the clinical evidence and guideline recommendations needed to ensure evidence-based ADC selection and sequencing. Presenters will discuss data from landmark trials and contextualize the application of these concepts through patient case scenarios. A key focus during this session will be on supporting patient safety through adverse effect (AE) identification and management, as ADC-related toxicities follow nontraditional timelines and vary drastically. Participants will examine how to integrate these clinical insights into practice by reviewing operational workflows for therapy verification, navigating look-alike/sound-alike risks, and implementing protocolized monitoring for early AE recognition. The session will also review best practices to optimize supportive care coordination to prevent premature dose interruptions and maximize treatment adherence.
Target audience: Oncology pharmacists
Type of activity: Application
Release date: July 30, 2026
Expiration date: July 30, 2027
Learner level: Intermediate, Advanced
Time to complete activity: 1.25 hours
Fee: Free
Educational Objectives
At the completion of this activity, participants will be able to:
- Examine emerging clinical evidence and guideline recommendations that support evidence-aligned selection and sequencing of antibody drug-conjugates (ADCs) across breast cancer subtypes and lines of therapy
- Apply ADC-specific toxicity profiles to guide appropriate prophylaxis, monitoring, and management strategies
- Identify practical strategies to optimize pharmacist workflows for therapy verification, safety monitoring, and coordination of supportive care across settings
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